Xenleta
Lefamulin Acetate
What is Xenleta used for?
This medication is used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
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Xenleta Frequently Asked Questions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Other medications can affect the removal of lefamulin from your body, which may affect how lefamulin works. Examples include azole antifungals (such as fluconazole, itraconazole), HIV protease inhibitors (such as nelfinavir), rifamycins (such as rifabutin, rifampin), ritonavir, St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Many drugs besides lefamulin may affect the heart rhythm (QT prolongation), including artemether/lumefantrine, dasatinib, dronedarone, eliglustat, entrectinib, midostaurin, mobocertinib, pimozide, quetiapine, tacrolimus, among others.
This medication can slow down the removal of other medications from your body, which may affect how they work. Examples include elacestrant, lomitapide, lonafarnib, among others.