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What is Xalkori used for?

Crizotinib is used to treat certain types of cancer (such as lung cancer, anaplastic large cell lymphoma-ALCL). It is also used to treat a certain type of tumor (inflammatory myofibroblastic tumor-IMT). Crizotinib works by slowing or stopping the growth of cancer or tumor cells. It belongs to a class of drugs known as kinase inhibitors.




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Xalkori Frequently Asked Questions

Read the Medication Guide and, if available, the Instructions for Use provided by your pharmacist before you start taking crizotinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. This medication comes in 2 dosage forms: a capsule to swallow or a capsule that must be opened that contains pellets.

If you are using the capsules to swallow, swallow the capsule(s) whole. Do not chew, crush, or split the capsules.

If you are using the capsules that contain pellets, do not swallow the capsule(s) whole. You must first open the capsule(s), then directly pour or spoon all of the pellets into your mouth. Do not chew or crush the pellets before swallowing. Drink water after taking to make sure the entire dose is taken. Repeat these steps if the dose is for more than one capsule. Throw away the empty capsule shell(s) in the trash.

If you vomit after taking your dose of the medication, do not take an extra dose. Take the next dose of your medication at the regular time.

The dosage is based on your medical condition, lab tests, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). For children, the dosage is also based on body size.

To decrease the risk of side effects, your doctor may prescribe other medications to take along with this medication. Carefully follow your doctor's directions for all your medications.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Xalkori Dosage and Form Information

250 Mg
200 Mg
Pellets In Dispensing Capsule
150 Mg
50 Mg
20 Mg