Back to Search Results


This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.
Vaginal Disorders


Rx icon

Learn more about price differences between brand and generic drugs

Get the Inside Rx app

Frequently Asked Questions

Estrogens, either used alone or with another hormone (progestin), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia.Estrogens can increase the risk of cancer of the uterus (endometrial cancer). Taking a progestin as directed by your doctor can help decrease this risk. Tell your doctor right away if you have any unusual vaginal bleeding.In postmenopausal women, estrogens can increase the risk of cancer of the ovaries, stroke, dementia, and serious blood clots in the legs. Estrogens alone do not appear to increase the risk of breast cancer when used for up to 7 years. Estrogen, when used with a progestin, can increase the risk of heart disease (such as heart attacks), stroke, serious blood clots in the lungs/legs, dementia, and cancer of the breast/ovaries.The risk for serious side effects may depend on the dose of estrogen and the length of time it is used. This medication should be used at the lowest effective dose and for the shortest amount of time. Discuss the use of this medication with your doctor and check with him/her regularly (for example, every 3 to 6 months) to see if you still need to take this medication. If you will be taking this medication long-term, you should have regular complete physical exams (for example, once a year) as directed by your doctor. See also Notes section.

Similar Drugs

Brand Name Examples Supplied As Strength
Climara Patch Transdermal Weekly 0.06Mg/24H0.05Mg/24H.025Mg/24H.0375Mg/24.075Mg/24H0.1Mg/24Hr
Divigel Gel In Packet 0.75/0.75G1 Mg/Gram0.25/0.25G0.5Mg/0.5G1.25/1.25G
Elestrin Gel In Metered-Dose Pump 0.87G
Estrace Cream With Applicator 0.01%
Tablet 1 Mg0.5 Mg2 Mg
Estring Ring Vaginal 7.5Mcg/24H
Estrogel Gel In Metered-Dose Pump 1.25 G
Evamist Spray Non-Aerosol 1.53/Spray
Imvexxy Insert Dose Pack 10 Mcg4 Mcg
Insert 4 Mcg10 Mcg
Menostar Patch Transdermal Weekly 14Mcg/24Hr
Minivelle Patch Transdermal Semiweekly 0.1Mg/24Hr0.05Mg/24H.075Mg/24H.0375Mg/24.025Mg/24H
Vagifem Tablet 10 Mcg
Vivelle-Dot Patch Transdermal Semiweekly .025Mg/24H.075Mg/24H0.05Mg/24H0.1Mg/24Hr.0375Mg/24
Generic Examples Supplied As Strength
Dotti Patch Transdermal Semiweekly .025Mg/24H0.05Mg/24H.0375Mg/24.075Mg/24H0.1Mg/24Hr
Estradiol Cream With Applicator 0.01%
Tablet 10 Mcg2 Mg1 Mg0.5 Mg
Gel In Packet 0.25/0.25G1 Mg/Gram0.75/0.75G1.25/1.25G0.5Mg/0.5G
Pellet 6 Mg
Estradiol (Once Weekly) Patch Transdermal Weekly 0.1Mg/24Hr0.06Mg/24H.025Mg/24H.0375Mg/240.05Mg/24H.075Mg/24H
Estradiol (Twice Weekly) Patch Transdermal Semiweekly .075Mg/24H0.1Mg/24Hr.0375Mg/24.025Mg/24H0.05Mg/24H
Lyllana Patch Transdermal Semiweekly 0.05Mg/24H.025Mg/24H.0375Mg/24.075Mg/24H0.1Mg/24Hr
Yuvafem Tablet 10 Mcg

Save up to 80% on brand & generic medications.