Back to Drug Directory


Oxymetazoline Hcl/Pf

What is Upneeq used for?

This medication is used to treat a certain eyelid condition (acquired blepharoptosis) that causes drooping upper eyelid(s). It belongs to a class of drugs known as alpha agonists. Oxymetazoline works by making a certain eyelid muscle get shorter and tighter (contract).


Oxymetazoline Hcl/Pf


Ophthalmic Conditions
InsideRx Coupon Icon

Get Upneeq Savings

Upneeq prices starting at $239.78.

Upneeq Frequently Asked Questions

Read the Instructions for Use leaflet if available from your pharmacist before you start using oxymetazoline and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Use this medication in the affected eye(s) as directed by your doctor, usually 1 drop in the affected eye(s) once daily.

To apply eye drops, wash hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

If you are wearing contact lenses, remove them before using eye drops. Wait at least 15 minutes before replacing your contact lenses. Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. Look downward, gently close your eyes, and place one finger at the corner of your eye (near the nose). Apply gentle pressure for 1 to 2 minutes before opening your eyes. This will prevent the medication from draining out. Try not to blink or rub your eye. If a drop misses your eye, try again. If directed to use this medication in both eyes, repeat these steps for your other eye. After you have applied the daily dose of oxymetazoline, throw away the single-use container. Do not save any unused medication left in the single-use container.

Before using, check this product visually. Do not use if the liquid has changed color or is cloudy.

If you are using another kind of eye medication (such as drops or ointments), wait at least 15 minutes before applying other medications. Use eye drops before eye ointments to allow the drops to enter the eye.

Wait several minutes for your vision to clear before driving or operating machinery.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

Tell your doctor if your condition does not get better or if it gets worse.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Upneeq Dosage and Form Information

Dropperette Single-Use Drop Dispenser
0.1 %