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What is Trikafta used for?

This product has 2 different tablets. One tablet contains 3 medications (it is a "multi-drug"): elexacaftor, tezacaftor, and ivacaftor. The other tablet contains only ivacaftor. This product is used to treat cystic fibrosis in certain people (those with an abnormal "CFTR" gene). It may help to improve breathing, reduce the risk of lung infections, and improve weight gain.




Cystic Fibrosis
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Trikafta Frequently Asked Questions

Read the Patient Information Leaflet if available from your pharmacist before you start taking this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take these medications by mouth as directed by your doctor, usually 2 multi-drug tablets in the morning, and 1 ivacaftor tablet about 12 hours later in the evening. Take the tablets with food that contains fat. Some examples are eggs, meat, nuts, butter, peanut butter, whole-milk dairy products (such as whole milk, cheese, yogurt).

The manufacturer directs to swallow this medication whole. However, many similar drugs (immediate-release tablets) can be split/crushed. Follow your doctor's directions on how to take this medication.

The dosage is based on your medical condition, age, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Use this product regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Tell your doctor if you do not get better or if you get worse.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Trikafta Dosage and Form Information

Tablet Seq
Granules In Packet Sequential