Back to Search Results


This medication is used to treat low levels of salt (sodium) in the blood, which can result from conditions such as heart failure and certain hormone imbalances. Tolvaptan belongs to a class of drugs known as vasopressin receptor antagonists. It works by increasing the amount of urine you make, causing your body to get rid of extra water. This helps to slowly increase to normal levels of salt in the blood.Different brands of this medication have different uses. Do not change brands of this medication unless directed by your doctor.
Kidney Disease


Rx icon

Learn more about price differences between brand and generic drugs

Get the Inside Rx app

Frequently Asked Questions

Treatment with this drug should be started or restarted in a hospital for proper monitoring. If your level of sodium in the blood is raised too quickly, it may cause a serious (even fatal) condition called osmotic demyelination syndrome. The risk is higher if you have liver disease, poor nutrition, or if you use/abuse alcohol. Tell your doctor right away if you have symptoms such as trouble speaking/swallowing, mental/mood changes (such as confusion), weakness/involuntary movement in the arms/legs, or seizures.Do not use this medication to treat a certain kidney problem (autosomal dominant polycystic kidney disease-ADPKD). Due to the risk of serious liver damage, you must be in a special program for you to take this medication to treat ADPKD. Ask your doctor for details.

Similar Drugs

Brand Name Examples Supplied As Strength
Jynarque Tablet Seq 30 Mg-15Mg90 Mg-30Mg15 Mg-15Mg60 Mg-30Mg45 Mg-15Mg
Tablet 30 Mg15 Mg
Samsca Tablet 15 Mg30 Mg
Generic Examples Supplied As Strength
Tolvaptan Tablet 15 Mg30 Mg

Save up to 80% on brand & generic medications.