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What is Retevmo used for?

This medication is used to treat certain types of cancer (such as lung cancer, thyroid cancer, medullary thyroid cancer, certain other solid tumors). Selpercatinib belongs to a class of drugs known as kinase inhibitors. It works by slowing or stopping the growth of cancer cells.




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Retevmo Frequently Asked Questions

Read the Patient Information Leaflet if available from your pharmacist before you start taking selpercatinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice daily (every 12 hours). Swallow the capsules whole. Do not crush or chew the capsules.

The dosage is based on your weight, medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). If you have certain side effects, your doctor may adjust your dose or stop treatment for some time.

Medications which reduce or block stomach acid (such as proton pump inhibitors-PPIs, H2 blockers, antacids) may reduce the absorption of selpercatinib, making it work less well. If you take a PPI (such as omeprazole, lansoprazole), take selpercatinib with food. If you take an antacid, take selpercatinib at least 2 hours before or 2 hours after taking the antacid. If you take a H2 blocker (such as famotidine, ranitidine), take selpercatinib at least 2 hours before or at least 10 hours after taking the H2 blocker.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of serious side effects will increase.

If you vomit your dose of selpercatinib, do not take another dose. Take your next dose at your regular scheduled time. Do not take two doses at the same time.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Retevmo Dosage and Form Information

40 Mg
80 Mg