Back to Drug Directory



What is Palynziq used for?

This medication is used by people with a certain inherited condition (phenylketonuria) to reduce high levels of a certain substance (phenylalanine) that builds up in the blood. Having high levels of phenylalanine in the blood may cause brain damage, heart problems, an abnormally small head size, and behavioral problems. Pegvaliase works by breaking down phenylalanine in the blood. Along with using this medication, you should follow a special diet to control your blood phenylalanine levels. Ask your doctor for details.




Enzyme Deficiencies
InsideRx Coupon Icon

Get Palynziq Savings

Compare prices for Palynziq and save up to 80%.

The Savings Card works just like a coupon!

Palynziq Frequently Asked Questions

This medication has caused serious allergic reactions which can be life-threatening. This reaction can happen at any time during treatment. Get medical help right away if you notice any symptoms of a serious allergic reaction, including: flushing/rash, itching/swelling (especially of the face, tongue, throat), severe dizziness, trouble breathing, fast heartbeat, fainting, chest discomfort/tightness, nausea, vomiting, or diarrhea. To be sure that you do not have a serious reaction, you will need to stay in a health care setting (such as a doctor's office) for at least 1 hour after taking this drug for the first time so your doctor can carefully monitor you and provide medical help if needed.

After the first injection, you and your doctor may decide you can use this medication at home. Your health care provider will instruct you and/or your caregiver how to inject this medication the right way.

Your doctor will also prescribe another medication (epinephrine) in case you have a serious allergic reaction outside the health care setting. Read the Patient Information Leaflet for this medication provided by your pharmacist. Learn ahead of time when and how to use your brand of epinephrine. If you have to use it, get medical help as soon as you have used it.

To receive this medication in the United States, you must understand, agree to, and carefully follow the requirements of the Palynziq REMS Program. If you live in Canada or any other country, consult your doctor and pharmacist for your country's regulations.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Palynziq Dosage and Form Information

2.5 Mg/0.5
20 Mg/Ml