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What is Oxervate used for?

This medication is used to treat a certain eye disorder (neurotrophic keratitis) that causes a loss of nerve function to a certain part of your eye (the cornea). Cenegermin is a man-made form of a substance made by your body. It is used by your body to help maintain and make more nerve cells in your eyes. This medication may help prevent decreased vision or loss of vision caused by neurotrophic keratitis.




Ophthalmic Conditions
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Oxervate Frequently Asked Questions

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is stored in a freezer at the pharmacy. If you start treatment right away after receiving the weekly carton, you will have to wait until the first vial is thawed, which could take up to 30 minutes at room temperature. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water.

Use this medication in the affected eye(s) as directed by your doctor, usually 6 times a day, about 2 hours apart starting in the morning.

To apply eye drops, wash hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.

Take a vial out of the refrigerator and follow the manufacturer's directions to prepare and use this medication. If you are directed to use this medication in both eyes, you will need to use 2 vials each day. After you open a vial for use, connect the vial adapter as directed. The opened vial can be put back in the refrigerator for up to 12 hours. If needed, the opened vial may also be stored at room temperature for up to 12 hours. Do not freeze or shake the vial. Carefully follow the directions to use the single-use pipette dropper with the vial.

If you are wearing contact lenses, remove them before using eye drops. Wait at least 15 minutes before replacing your contact lenses. Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. With your head tilted back, blink a few times so that the medicine covers the surface of your eye. Look downward, gently close your eyes, and place one finger at the corner of your eye (near the nose). Apply gentle pressure for 1 to 2 minutes before opening your eyes. This will prevent the medication from draining out. Try not to rub your eye. If directed to use this medication in both eyes, repeat these steps for your other eye. Only use 1 pipette dropper for each eye and each dose. Throw away the used pipette dropper right away after use. If you miss your eye and there is no longer any eye drop solution in the dropper, try again, using a new pipette dropper.

Throw away the used vial at the end of each day (after 12 hours) even if there is still some eye drop solution left in it.

If you are using another kind of eye medication (such as drops or ointments), wait at least 15 minutes before applying other medications. Use eye drops before eye ointments to allow the drops to enter the eye.

Wait several minutes for your vision to clear before driving or operating machinery.

Use this medication regularly to get the most benefit from it. To help you remember, you may want to set an alarm as a reminder for dosing. Mark the provided weekly dose recording card to track each time you use a dose. Continue to use this medication for the full time prescribed (usually 8 weeks).

Tell your doctor if your condition does not get better or if it gets worse.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Oxervate Dosage and Form Information

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