You should not take Korlym if you are allergic to mifepristone.
You should not take Korlym if you are a woman who still has her uterus and you have:
- endometrial hyperplasia (changes in the cells lining your uterus);
- endometrial cancer (cancer of the cells lining your uterus); or
- unusual or unexplained vaginal bleeding.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with mifepristone. Your doctor may change your treatment plan if you also use:
- cyclosporine;
- dihydroergotamine, ergotamine;
- fentanyl;
- lovastatin, simvastatin;
- pimozide;
- quinidine;
- sirolimus, tacrolimus; or
- steroid medicine (dexamethasone, prednisone, methylprednisolone, and others).
Tell your doctor if you have ever had:
- low levels of potassium in your blood;
- heart disease;
- a bleeding or blood-clotting disorder;
- liver or kidney disease;
- an organ transplant; or
- a problem with your adrenal glands.
You will need to have a negative pregnancy test before you start taking Korlym, or if you restart the medicine after not taking it for longer than 2 weeks.
Do not use mifepristone if you are pregnant. It could harm the unborn baby or cause a miscarriage. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 1 month after your last dose.
Mifepristone can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using mifepristone, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 21 days after your last dose. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Mifepristone is not approved for use by anyone younger than 18 years old.