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Crysvita

Burosumab-Twza
Burosumab is a monoclonal antibody that targets and blocks the activity of a blood protein called FGF23. In a genetic condition called X-linked hypophosphatemia (HYE-poe-fos-fa-TEEM-ee-a), low phosphate levels in blood are caused by abnormally high levels of FGF23 protein, which causes the kidneys to stop reabsorbing phosphate into the bloodstream. Blocking the FGF23 protein allows the kidneys to restore and maintain normal phosphate levels. Phosphate is important for the strength of your bones and teeth. Low phosphate levels can lead to bone deformities and growth problems. Burosumab is used to normalize phosphate levels in adults and children who are at least 1 year old and have X-linked hypophosphatemia. Burosumab may also be used for purposes not listed in this medication guide.
CHEMICAL NAME
Burosumab-Twza
DRUG TYPE
Endocrine Disorders
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Frequently Asked Questions

You should not use burosumab if you have severe kidney disease, or if you currently take phosphate or vitamin D by mouth.

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