Nucala

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Do not share this medication with others.

Keep all medical and lab appointments.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Read the Patient Information Leaflet and Instructions for Use if available from your pharmacist before you start using mepolizumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is used by injection under the skin into the upper arm, thigh, or abdomen. It is used as directed by your doctor, usually once every 4 weeks. The dosage is based on your age, medical condition and response to treatment.

If you are using the syringe/autoinjector, take it out of the refrigerator before use. Let it warm up to room temperature for at least 30 minutes. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. Do not shake this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into areas of skin that are tender, bruised, red, or hard.

If you are regularly using a corticosteroid medication, you should not stop using it unless directed by your doctor. Some conditions (such as asthma, allergies) may become worse when the drug is suddenly stopped. If you suddenly stop using the corticosteroid medication, you may also have withdrawal symptoms (such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness). To help prevent withdrawal, your doctor may slowly lower the dose of your corticosteroid medication after you begin using mepolizumab. Tell your doctor or pharmacist right away if you have withdrawal.

Use this medication regularly to get the most benefit from it. To help you remember, mark your calendar when you need to use it each month.

Learn how to store and discard medical supplies safely.

Tell your doctor if your condition does not get better or if it gets worse.

Before using mepolizumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: infection due to a parasite.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Store the syringe/autoinjector in the original package in the refrigerator. Protect from light. Do not freeze. If needed, the unopened carton can be stored at room temperature for up to 7 days. Once the syringe/autoinjector is removed from the carton, use within 8 hours. Discard if not used within 8 hours. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.