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This medication is given by injection under the skin by a health care professional. It is given as directed by your doctor, usually 10 to 14 hours before the blood filtering procedure.

The dosage is based on your medical condition and weight.

Motixafortide may cause serious (sometimes fatal) allergic reactions, usually within 30 minutes after the injection. To help prevent these side effects, your doctor will prescribe other medications (such as diphenhydramine, montelukast, and an H2 blocker) for you to receive before each dose. Carefully follow your doctor's instructions. Your health care professional will also closely monitor you for 1 hour after the injection. Get medical help right away if you notice any signs of a serious allergic reaction such as rash, itching/swelling (especially of the face, tongue, throat), severe dizziness, trouble breathing, flushing, chills, nausea, or vomiting.

See also How to Use section.

Pain, redness, or itching at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Motixafortide can commonly cause a rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Get medical help right away if you develop any rash.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Lab and/or medical tests (such as complete blood count) should be done while you are using this medication. Keep all medical and lab appointments. Consult your doctor for more details.

It is important to get each dose of this medication as scheduled. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule.

Not applicable. This medication is given in a hospital or clinic or doctor's office and will not be stored at home.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.