Side effects, images, and drug details for Hydrochlorothiazide-Lisinopril - Inside Rx
Back to Search Results


Hydrochlorothiazide is a thiazide diuretic (water pill). Lisinopril is in an ACE inhibitor (ACE stands for angiotensin converting enzyme). Hydrochlorothiazide and lisinopril is a combination medicine used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack. Hydrochlorothiazide and lisinopril may also be used for purposes not listed in this medication guide.
ACE inhibitors with thiazides


Frequently Asked Questions

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medication that contains aliskiren (a blood pressure medicine).

Similar Drugs

Brand Name Examples Supplied As Strength
Zestoretic tablet 12.5 mg-10 mg12.5 mg-20 mg25 mg-20 mg
Generic Examples Supplied As Strength
Hydrochlorothiazide-Lisinopril tablet 12.5 mg-10 mg12.5 mg-20 mg25 mg-20 mg

Save up to 80% on brand & generic medications.